Table 1 Comparison of de novo fatty acid synthesis (lipogenesis), fat deposition, and lipoproteins in various species

Items Species
Poultry (chicken) Monogastric animals (pigs) Rodents (rats, mice) Ruminants(cattle) Primates(humans)
Major site of lipogenesis Liver Adipocytes Liver/Adipocytes Adipocytes Liver
Secondary site of lipogenesis - Liver - - Adipocytes
Primary substrate for lipogenesis Glucose Glucose Glucose Acetate Glucose
Major site of fat deposition Visceral and abdominal fat,oocytes (laying hens) Visceral, subcutaneous and intramuscular fat Visceral and subcutaneous fat Subcutaneous and intramuscular fat Visceral and subcutaneous fat
Lipoprotein(protomicron/chylomicron) Protomicron Chylomicron Chylomicron Chylomicron Chylomicron
Intestine to blood Intestine to lymph Intestine to lymph Intestine to lymph Intestine to lymph
Lipoprotein(VLDL) Liver to periphery and ovary Liver to peripheral tissues Liver to peripheral tissues Liver to peripheral tissues Liver to peripheral tissues
Others Lipogenesis is important for egg formation. - - Mammary gland is major site of lipogenesis in lactating ruminants. -